Presentation Abstract: The Empathy Deficit in the Treatment of Depressed Patients and The Inflammation-Depression Connection Approach, 4th Anti-Aging And Regenerative Medicine Conference, Bangkok, Thailand, 2012

Depression ICD-9 296.3

Presentation Abstract

Title: The Empathy Deficit in the Treatment of Depressed Patients and The Inflammation-Depression Connection Approach
To be presented at the 4th American Academy in Anti-Aging And Regenerative Medicine and 2nd Congress On Anti-Aging and Aesthetic MedicineSeptember 7-9, 2012Bangkok, Thailand
By Dr. James Stoxen DC President, Team Doctors Treatment and Training Center

You can watch the entire lecture here –> LECTURE


Depression represents a major public health problem it is estimated that up to 16 – 20% of the population has had depression at any one time and that 5 to 7% of the population is assumed to suffer from major depression. Studies have also shown that there is a correlation between chronic depression and the development of Alzheimer’s, Parkinson’ and dementia in later life.

There is substantial literature linking inflammation with the risk for depression. The purpose of my presentation is to list the inflammatory mediators and their link to depression. Patients with inflammatory disorders such as MS, cardiovascular disorders, rheumatoid arthritis, osteoarthritis

Increase inflammatory cytokine expression and the development of concurrent psychiatric symptoms were initially observed after administration of cytokine therapy to patients afflicted with cancer hepatitis and MS. It has been found that patients with depression have high levels of inflammatory biomarkers. This suggests that inflammation can be a mediator for depression.

The purpose of this presentation is to review these studies and determine their potential to lead to interventions which may reduce the risks for inflammatory diseases of aging such as osteoarthritis cardiovascular disease and his symptoms related to varying degrees of depression.

Depression it is obviously a stress sensitive disorder however the actual causal mechanism for their relationship is unknown. Research team led by Carnegie melon University’s Sheldon: has found that chronic psychological stresses associated with the bodies losing its ability to regulate the inflammatory response which can promote the development and progression of the disease called depression. So while inflammation can cause or be linked to depression, and the stress and depression can also be linked back to inflammation.

Aging is also associated with increased likelihood of chronic pain and inflammatory conditions. A part despite improving knowledge is of underlying mechanisms of chronic pain many patients who have chronic pain receive inadequate care both short-term and long-term. We are going to discuss some novel ways to reduce chronic pain, chronic inflammation and disability dust reducing overall inflammation and possibly reducing the risk of the development and exacerbation of chronic depression.

We will also discuss the treatments, which can and may reduce depression. Currently antidepressants only produced remission and 30% of patients. The part of the problem is that the pathophysiology of depression has not been well understood and treatments are based on empirical data and not on the mechanisms or causes of action. Many research studies suggest that addressing pro-inflammatory cytokine production represents a possible strategy to treat depression besides the use of psychotropic drugs.

This will include the relationship between dietary influences and the risk of depression, and fatty acid supplementation for the fresh and add the adiposity risk factors for childhood and adult onset depression. I will also discuss the role of inactivity in inflammation and end depression as well as the effects of exercise and the increase and decrease of inflammation associated with exercise.

I will discuss natural ways to decrease levels of systemic inflammation both from a treatment and preventive approach to use with or without psychotropic drugs.


Dr Stoxen is a #1 International Best Selling Author. He is the president of Team Doctors®, Treatment and Training Center Chicago, one of the most recognized treatment centers in the world. He is a much sought-after speaker giving over 1000 live presentations and has lectured at over 70 medical conferences to over 50,000 doctors in more than 20 countries. He’s been asked to be the keynote speaker to specifically lecture on his human spring approach to thoracic outlet syndrome and other medical conditions. After his groundbreaking lecture on the Integrated Spring-Mass Model at the World Congress of Sports and Exercise Medicine he was presented with an Honorary Fellowship Award by a member of the royal family, the Sultan of Pahang, for his distinguished research and contributions to the advancement of Sports and Exercise Medicine on an International level. (Full Bio) Dr Stoxen can be reached directly at

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